ProSilience™ HU58™
A stable probiotic with scientifically
validated benefits

An innovative solution for brands developing
competitive, differentiated functional products.
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Explore the solution ProSilience™ HU58™ A stable probiotic with
scientifically validated
benefits
An innovative solution for brands developing competitive, differentiated
functional products.
Explore the solution
Tailored solutions
for the food & dietary
supplement industries
From microbial cultures to enzymes, we provide
practical solutions to our customers' challenges.
See how it works Tailored solutions for the food & dietary supplements From microbial cultures to enzymes,
we provide practical solutions to our
customers' challenges.
See how it works
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Seamless integration into
premium functional
foods
Easy to formulate, with no impact on taste or texture.
Seamless integration
into premium functional
foods
Easy to formulate, with no impact
on taste or texture.
Request a sample

CONTEXT

The functional food market is growing, creating new opportunities for differentiation.

CURRENT MARKET CHALLENGES

Food & Beverage manufacturers face increasing challenges in ensuring product stability, product differentiation and consistent delivery of the health benefits promised to consumers.

PROCESSING
INSTABILITY


Most probiotics lose viability during thermal processing or over the product's shelf life.

LIMITED
DIFFERENTIATION


Without proven functional benefits, products quickly compete on price and promotional offers.

SENSORY
TRADE-OFFS


Many functional ingredients affect taste, texture or product clarity, creating formulation trade-offs.

Pressure for
innovation


Consumers increasingly expect products with proven health benefits integrated into everyday foods, not just supplements.

HU58™ SOLUTION

PROSILIENCE™ HU58™

Delivering a competitive advantage through stable probiotic performance in food applications.

Developed by Novonesis and distributed by Biocult, ProSilience™ HU58™is a stable probiotic designed for food and beverage manufacturers seeking reliable processing performance, probiotic viability and proven consumer benefits.

How ProSilience™ HU58™ works

ProSilience™ HU58™ is based on the probiotic strain Bacillus subtilis HU58™, a spore-forming bacterium recognized for its exceptional stability under demanding processing conditions.

Thanks to its spore-forming technology, the probiotic maintains its viability throughout processing and across the product's shelf life, without significantly affecting taste, texture or clarity.

The result: a stable, effective functional ingredient that is easy to integrate into innovative food applications.

4 key benefits

for functional product development

Connect with our experts and discover the unique benefits of ProSilience™ HU58™ today.

Why ProSilience™ HU58™ is more than just another probiotic

ProSilience™ HU58™ harnesses the spore-forming properties of the Bacillus subtilis HU58™ strain to deliver exceptional stability and viability in modern food and beverage applications.

Spore-forming technology: naturally resistant to processing and challenging formulation conditions.

Versatile applications: suitable for a wide range of food and beverage products.

Proven probiotic stability under challenging processing conditions

ProSilience™ HU58™ demonstrates superior pasteurization resistance compared to other sporulated strains used in Food & Beverage applications.

Under acidic conditions and thermal treatment (pH 3.5 + heat), ProSilience™ HU58™ maintained 99% probiotic viability after processing and storage, compared with only 7% for a standard Bacillus coagulans strain.

This exceptional stability supports the development of modern functional foods without compromising probiotic performance in the final product.

COMPETITIVE ADVANTAGES FOR MANUFACTURERS

Consumers are increasingly looking for products that combine an enjoyable eating and drinking experience with proven health benefits.

ProSilience™ HU58™ helps manufacturers develop modern functional foods and beverages with proven probiotic stability and performance tailored to today's processing requirements.

VALIDATED APPLICATIONS FOR PROSILIENCE™ HU58™

Suitable for a wide range of food and beverage applications while
maintaining probiotic stability across selected processes and product categories.

* Excellent stability during mixing, drying and selected thermal processes.

* Maintains probiotic viability throughout the product's shelf life.

* Compatible with solid formulations, including snacks, bars and functional cereals.

* No impact on the taste or texture of the final product.

* Supports functional differentiation and premium positioning.

* Direct integration into pasteurisation, HTST and HPP processes.

* No impact on taste, clarity or sensory experience.

* High probiotic stability in functional and fermented beverages.

* Ideal for functional waters, RTD coffee, kombucha, smoothies and alcohol-free beverages.

* Supports the development of products with digestive and immune health benefits.

INTEGRATION INTO FUNCTIONAL PRODUCTS

Discover how Danish kombucha producer Læsk enhanced its products with ProSilience™ HU58™.

According to Læsk, beyond the probiotic's outstanding thermal stability, Novonesis provides unrivalled commercial and regulatory support—an important advantage for operating in highly regulated markets such as Denmark.

Fermenta Plus
(alcohol-free beer)

Where fermentation meets innovation.

An alcohol-free beer enriched with a probiotic designed to withstand processing. A concept that shows how brewing tradition can evolve into functional products without compromising the consumer experience.

Fermenta Plus
(alcohol-free beer)

Where fermentation meets innovation.

An alcohol-free beer enriched with a probiotic designed to withstand processing. A concept that shows how brewing tradition can evolve into functional products without compromising the consumer experience.

Lemon Spark
(sparkling water)

More than hydration.

Functional waters are among the fastest-growing beverage categories. ProSilience™ HU58™ opens new opportunities to develop differentiated products that combine refreshment with functional health benefits.

ProCoffee
(coffee capsules)

Probiotics with your morning coffee.

Your morning coffee ritual can also support digestive health. Thanks to the exceptional stability of ProSilience™ HU58™, coffee becomes a new opportunity for functional product innovation.

ProCoffee
(coffee capsules)

Probiotics with your morning coffee.

Your morning coffee ritual can also support digestive health. Thanks to the exceptional stability of ProSilience™ HU58™, coffee becomes a new opportunity for functional product innovation.

Test ProSilience™ HU58™ in your applications.

Request a free sample or schedule a consultation with our team.

    * Indicative figures based on publicly available market reports and consumer insights.

    * Chart sources: MarketsandMarkets, Market Reports World, Ingredion Consumer Trends and Kerry Health & Nutrition Institute.

    Biocult, a Novonesis partner, delivering global biosolutions for better business, healthier lives and a healthier planet.